COT statements and position papers A-Z
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A
Acid sweets
Adverse reactions to acid sweets (2004)
External link to the national archive for the 2004 COT statement on adverse reactions to acid sweets
Acrylamide
Potential risks from acrylamide in the diet of infants and young children (2016)
External link to the national archive for the 2016 COT Statement on Acrylamide
Additives
Potassium-based replacements for sodium chloride and sodium-based additives (2017)
Health effects of mixtures of food additives (T01040/41) (2008)
Research project (TO7040) investigating the mixtures of certain food colours and a preservative on behaviour in children (2007)
Food additives and developmental neurotoxicity (2006)
Research project investigating the effect of food additives on behaviour (2002)
Aflatoxin
Alcohol
The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)
Allergic disease
Maternal and infant dietary exposures and allergy, and risk of development of atopic outcomes and autoimmune disease (2017)
Risks of chemical toxicity and allergic disease in relation to infant diet (2012)
Allergenic foods
The timing of introduction of allergenic foods (2016)
COT joint statement on the timing of introduction of gluten into the infant diet (2011)
Review of the 1998 COT recommendations on peanut avoidance (2008)
Aluminium
Addendum to the 2013 COT statement on Aluminium (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium
Potential risks from aluminium in the infant diet (2013)
External link to the national archive for the 2013 COT statement on Aluminium
Amnesic shellfish poisoning
Amnesic shellfish poisoning (ASP) (2001)
External link to the national archive for the 2001 COT statement on ASP
Arsenic
Statement on Arsenic in infants and young children (2016)
External link to the national archive for the 2016 COT statement on Arsenic
Arsenic in food: results of the 1999 total diet study (2003)
Aspartame
Current status of the randomized double-blind volunteer study on aspartame (2013)
External link to the national archive for 2013 COT position paper on aspartame
B
Bisphenols
Study of bisphenols in canned foods (2001)
Bisphenol A (1997)
External link to the national archive for the 1997 COT statement on bisphenol A
Bisphenol A diglycidyl ether (BADGE) in canned foods (1997)
External link to the national archive for the 1997 COT statement on BADGE in canned foods
Bitter apricot kernels
Cyanogenic glycosides in bitter apricot kernels (2006)
Bracken
Risk to consumers of eating foods derived from animals that have eaten bracken (2008)
Breast implants
Further toxicity studies in the rat of a hydrogel filler for breast implants (2006)
Further toxicity study in the rat of a hydrogel filler for breast implants (2002)
Toxicity study in the rat of a hydrogel filler for breast implants (2000)
Breast milk
Toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive (2004)
Health hazards of polychlorinated biphenyls (1997)
Bromine
Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)
Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)
Tetrabromobisphenol A - review of toxicological data (2004)
The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)
C
Cabin air environment
Review of possible adverse health effects in the crew of commercial aircraft (2013)
Review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft (2007)
Cadmium
The potential risks from cadmium in the infant diet (2018)
External link to the national archive for the 2018 COT statement on the potential risks from cadmium
Caffeine
The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)
Reproductive effects of caffeine (2008)
Reproductive effects of caffeine (2001)
Cannabidiol (CBD)
Position paper on the potential risk of CBD in CBD food products (2020)
COT position paper on the potential risk of cannabidiol (CBD) in CBD food products
Chlorine
Polychlorinated naphthalenes in food (2009)
Chlorinated paraffins in food (2009)
External link to the national archive for the 2009 COT statement on chlorinated paraffins in food
Chlorination disinfection by-products and risk of congenital anomalies in England and Wales (2008)
Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)
Chlorinated water and reproductive outcomes (2004)
Copper
Potential risks from copper in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on copper
CS
New formulation of CS - Sabre 540010-01 (2018)
Cyanide
D
Dental amalgam
Toxicity of dental amalgam (1997)
External link to the national archive for the 1997 COT statement on the toxicity of dental amalgam
Developmental neurotoxicity
Food additives and developmental neurotoxicity (2006)
Diet-drug interactions
COT/CSM one day meeting on diet-drug interactions (2006)
Diethyl-m-toluamide (DEET)
Review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET) (2006)
Review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET) (2002)
Dioxins
Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)
FSA funded study investigating the developmental effects of dioxin (TCDD) in rats (2007)
2005 WHO equivalency factors for dioxins and dioxin-like compounds (2006)
Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)
Dietary exposure to dioxins and dioxin-like PCBs (2000)
Dioxins and dioxin-like PCBs in free-range eggs (2000)
Disinfectants
Chlorination disinfection by-products and risk of congenital anomalies in England and Wales (2008)
Commercial survey investigating the occurrence of disinfectants and disinfection by-products in prepared salads (2006)
E
Eggs
Dioxins and dioxin-like PCBs in free-range eggs (2000)
Elements
Results of a multi-element survey of fungi and blackberries (2000)
Results of multi-element surveys (1998)
COT statement on the results of multi-element surveys
Endosulfan isomers, pentachlorobenzene and chlordecone
Endosulfan isomers, pentachlorobenzene and chlordecone (2014)
E(N)NDS – e-cigarettes
Statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Lay summary of statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Framework for risk assessment of flavouring compounds in E(N)NDS – e-cigarettes (2020)
COT framework for risk assessment of flavouring compounds in electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes)
Energy drinks
The potential risks from “energy drinks” in the diet of children and adolescents (2019)
COT statement on Energy drinks
Lay summary on the potential risks from “energy drinks” in the diet of children and adolescents (2019)
Lay summary COT statement on Energy drinks
Interim position paper on potential risks from “energy drinks” in the diet of children and adolescents (2018)
External link to the national archive for the 2018 COT interim position paper on energy drinks
Epigenetics
Statement from a joint Committee workshop on the use of epigenetics in chemical risk assessment (2019)
Workshop on transgenerational epigenetics (2008)
F
Fish and shellfish
Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)
Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)
Survey of mercury in fish and shellfish update (2004)
Survey of mercury in fish and shellfish (2003)
Amnesic shellfish poisoning (2001)
External link to the national archive for the 2001 COT statement on ASP
Results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products (1999)
Surveillance for malachite green and leucomalachite green in farmed fish (1999)
Fluorine
Fluorine in the 1997 Total Diet Study (2003)
The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)
Folic acid
Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)
COT statement on Folic Acid
Lay summary Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)
Lay summary COT statement on Folic Acid
Position paper on the current upper level for folic acid intake (2018)
G
Genetic modification
Studies of potatoes genetically modified to produce Galanthus nivalis lectin (2000)
Studies of potatoes genetically modified to produce Galanthus nivalis lectin (1999)
Genomics and Proteomics
Symposium of the use of Genomics and Proteomics in Toxicology (2002)
Glucosamine
Glucosamine and hepatotoxicity (2009)
External link to the national archive for the 2009 COT statement on glucosamine and hepatotoxicity
Gluten
COT joint statement on the timing of introduction to gluten into the infant diet (2011)
H
Halogenated contaminants
Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)
Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)
Hepatotoxicity
Glucosamine and hepatotoxicity (2009)
External link to the national archive for the 2009 COT statement on glucosamine and hepatotoxicity
Hexabromocyclododecanes (HBCDDs)
Addendum to the 2015 COT Statement on hexabromocyclododecanes (HBCDDs) (2016)
External link to the national archive for the 2016 Addendum to the 2015 COT statement on HBCDDs
Hexabromocyclododecanes (HBCDDs) (2015)
External link to the national archive for the 2015 COT statement on (HBCDDs)
Hexachlorobutadiene
Hexachlorobutadiene (2000)
External link to the national archive for the 2000 COT statement on Hexachlorobutadiene
Hexachlorocyclohexanes
Hexachlorocyclohexanes (HCHs) (2014)
External link to the national archive for the 2014 COT statement on HCHs
Hydrolysed formula
Hydrolysed cows' milk formulae (2016)
External link to the national archive for the 2016 COT statement on hydrolysed cows' milk formulae
I
Idiopathic Environmental Intolerance (IEI)
Idiopathic Environmental Intolerance (IEI) (2011)
External link to the national archive for the 2011 COT statement on IEI
Infant food and formulae
Addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)
Addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
Lay summary addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)
Lay summary addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
Overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)
COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
Lay summary overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)
Lay summary COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
The health effects of manganese in the diets of infants and young children (2018)
The results of the 2014 survey of metals and other elements in infant foods (2018)
Potential risks from nickel in the diet of infants and young children (2018)
The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)
T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants and young children (2018)
The potential risks from cadmium in the infant diet (2018)
External link to the national archive for the 2018 COT statement on the potential risks from cadmium
Potential risks from methylmercury in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on methylmercury
The potential risks from excess iodine (2017)
Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)
Maternal and infant dietary exposures and allergy, and risk of development of atopic outcomes and autoimmune disease (2017)
Hydrolysed cows' milk formulae (2016)
External link to the national archive for the 2016 COT statement on hydrolysed cows' milk formulae
The timing of introduction of allergenic foods (2016)
Statement on Arsenic in infants and young children (2016)
External link to the national archive for the 2016 COT statement on Arsenic
Potential risks from acrylamide in the diet of infants and young children (2016)
External link to the national archive for the 2016 COT Statement on Acrylamide
Addendum to the 2013 COT statement on lead (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead
Addendum to the 2013 COT statement on Aluminium (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium
Polybrominated biphenyls (PBBs) in the infant diet (2015)
External link to the national archive for the 2015 COT statement on PBBs in the infant diet
Polybrominated diphenyl ethers (PBDEs) (2015)
External link to the national archive for the 2015 COT statement on PBDEs
Hexabromocyclododecanes (HBCDDs) (2015)
External link to the national archive for the 2016 Addendum to the 2015 COT statement on (HBCDDs)
Risks from Perfluorooctane (PFOS) in the infant diet 2014
External link to the national archive for the 2014 COT statement on PFOS
Endosulfan isomers, pentachlorobenzene and chlordecone (2014)
Hexachlorocyclohexanes (HCHs) (2014)
External link to the national archive for the 2014 COT statement on HCHs
Phytoestrogens (2013)
External link to the national archive for the 2013 COT statement on phytoestrogens
High levels of vitamin A in the infant diet (2013)
External link to the national archive for the 2013 COT statement on vitamin A in the infant diet
Potential risks from lead in the infant diet (2013)
External link to the national archive for the 2013 COT statement on lead
Potential risks from aluminium in the infant diet (2013)
External link to the national archive for the 2013 COT statement on aluminium in the infant diet
Risks of chemical toxicity and allergic disease in relation to infant diet (2012)
COT joint statement on the timing of introduction of gluten into the infant diet (2011)
Uranium levels in water used to reconstitute infant formula (2006)
Metals in infant food (2003)
External link to the national archive for the 2003 COT statement on metals in infant food
Phthalates in infant formulae (1996)
External link to the national archive for the 1996 COT statement on phthalates in infant formulae
Iodine
The potential risks from excess iodine (2017)
The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)
Iodine in cows' milk (2000)
External link to the national archive for the 2000 COT statement on iodine in cows' milk
Iodine in cows' milk (1997)
External link to the national archive for the 1997 COT statement on iodine in cows' milk
Irritant sprays
Guidance on information required by COT for consideration of irritant sprays and their formulation (2018)
J
No statements yet
K
No statements yet
L
Landfill sites
COT second statement on landfill sites (2010)
External link to the national archive for the 2010 COT second statement on landfill sites
Study by the small Area Health Statistics Unit (SAHSU) on health outcomes in population living around landfill sites (2001)
Also see the COT landfill statement
Lay summaries
Lay summary of the statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)
Lay summary of statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Lay summary addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)
Lay summary addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
Lay summary overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)
Lay summary COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years
Lay summary Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)
Lay summary COT statement on Folic Acid
Lay summary on the potential risks from “energy drinks” in the diet of children and adolescents (2019)
Lay summary COT statement on Energy drinks
The potential risks from cadmium in the infant diet (2018)
External link to the national archive for the 2018 COT statement on the potential risks from cadmium
Potential risks from copper in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on copper
The health effects of manganese in the diets of infants and young children (2018)
The results of the 2014 survey of metals and other elements in infant foods (2018)
Potential risks from nickel in the diet of infants and young children (2018)
The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)
Potential risks from methylmercury in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on methylmercury
Heat not burn tobacco products (2017)
External link to the national archive for the 2017 COT statement on heat not burn tobacco products
Addendum to the 2013 COT statement on potential risks from vitamin A (2017)
The potential risks from excess iodine (2017)
Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)
Potassium-based replacements for sodium chloride and sodium-based additives (2017)
Addendum to the 2013 COT statement on lead (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead
Potential risks from acrylamide in the diet of infants and young children (2016)
External link to the national archive for the 2016 COT Statement on Acrylamide
Statement on Arsenic in infants and young children (2016)
External link to the national archive for the 2016 COT statement on arsenic
Addendum to the 2015 COT Statement on hexabromocyclododecanes (HBCDDs) (2016)
Polybrominated diphenyl esters (PBDEs) (2015)
External link to the national archive for the 2015 COT statement on PBDEs
Polybrominated biphenyls (PBBs) in the infant diet (2015)
External link to the national archive for the 2015 COT statement on PBBs in the infant diet
Hexabromocyclododecanes (HBCDDs) (2015)
External link to the national archive for the 2015 COT statement on HBCDDs
Domoic acid in king scallops (Pecten Maximus) (2014)
Risks from Perfluorooctane (PFOS) in the infant diet 2014
External link to the national archive for the 2014 COT statement on PFOS
Statement on Organophosphates (2014)
External link to the national archive for the 2014 COT statement on Organophosphate
Endosulfan isomers, pentachlorobenzene and chlordecone (2014)
Hexachlorocyclohexanes (HCHs) (2014)
External link to the national archive for the 2014 COT statement on HCHs
The possible harmful effects of high intakes of vitamin D (2014)
External link to the national archive for the 2014 COT statement on Vitamin D
High levels of vitamin A in the infant diet (2013)
External link to the national archive for the 2013 COT on vitamin
Statement on Phytoestrogens (2013)
External link to the national archive for the 2013 COT statement on phytoestrogens
Potential risks from lead in the infant diet (2013)
External link to the national archive for the 2013 COT statement on lead
Risks of chemical toxicity and allergic disease in relation to infant diet (2012)
The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)
Use of toxicogenomics in risk assessment (2012)
Dietary exposure to Phthalates - data from the Total Diet Study (2011)
Para-occupational exposure to pesticides and health outcomes (2011)
Effects of chronic dietary exposure to methanol (2011)
Proposal for restriction: DEHP, BBP, DBP DiBP (2011)
Idiopathic Environmental Intolerance (IEI) (2011)
External link to the national archive for the 2011 COT statement on IEI
Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)
Review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft (2007)
Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)
Lead
Addendum to the 2013 COT statement on lead (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead
Potential risks from lead in the infant diet (2013)
External link to the national archive for the 2013 COT statement on lead
M
Manganese
The health effects of manganese in the diets of infants and young children (2018)
Malachite green
Surveillance for malachite green and leucomalachite green in farmed fish (1999)
Male reproduction
Developmental and function in adulthood of the human male reproductive system - potential chemical-induced effects (2006)
Male reproduction (2004)
External link to the national archive for the 2004 COT statement on male reproduction
Marine biotoxins
Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)
Amnesic shellfish poisoning (ASP) (2001)
External link to the national archive for the 2001 COT statement on ASP
Mercury
Survey of mercury in fish and shellfish update (2004)
Survey of mercury in fish and shellfish (2003)
Toxicity of dental amalgam (1997)
External link to the national archive for the 1997 COT statement on the dental amalgam
Metals
The health effects of manganese in the diets of infants and young children (2018)
The results of the 2014 survey of metals and other elements in infant foods (2018)
The potential risks from cadmium in the infant diet (2018)
External link to the national archive for the 2018 COT statement on the potential risks from cadmium
Potential risks from nickel in the diet of infants and young children (2018)
Potential risks from copper in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on copper
Addendum to the 2013 COT statement on lead (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead
Addendum to the 2013 COT statement on Aluminium (2016)
External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium
Potential risks from aluminium in the infant diet (2013)
External link to the national archive for the 2013 COT statement on aluminium
Potential risks from lead in the infant diet (2013)
External link to the national archive for the 2013 COT statement on lead
2006 Total Diet Study - metals and other elements (2008)
Uranium levels in water used to reconstitute infant formula (2006)
2000 Total Diet Study - 12 metals and other elements (2004)
Survey of mercury in fish and shellfish update (2004)
Survey of mercury in fish and shellfish (2003)
Metals in infant food (2003)
External link to the national archive for the 2003 COT statement on metals in infant food
Results of a multi-element survey of fungi and blackberries (2000)
Results of multi-element surveys (1998)
Toxicity of dental amalgam (1997)
External link to the national archive for the 1997 COT statement on the toxicity of dental amalgam
Methanol
Effects of chronic dietary exposure to methanol (2011)
Methylglyoxal
Methylglyoxal (2009)
External link to the national archive for the 2009 COT statement on methylglyoxal
Methylmercury
Potential risks from methylmercury in the diet of infants and young children (2018)
External link to the national archive for the 2018 COT statement on methylmercury
Microbiota
Statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)
Lay summary of the statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)
Microplastics
Overarching statement on the potential risks from exposure to microplastics (2021)
Lay summary overarching statement on the potential risks from exposure to microplastics (2021)
Milk
Toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive (2004)
Iodine in cows' milk (2000)
External link to the national archive for the 2000 COT statement on iodine in cows' milk
Iodine in cows' milk (1997)
External link to the national archive for the 1997 COT statement on iodine in cows' milk
Health hazards of polychlorinated biphenyls (1997)
Mycotoxins
T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants and young children (2018)
The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)
Surveillance for the mycotoxin moniliformin (1998)
Surveillance for the mycotoxin sterigmatocystin (1998)
Ochratoxin A on dried vine fruits (1997)
N
Nanomaterial toxicology
Addendum to Joint statement on nanomaterial toxicology (2007)
Joint statement on nanomaterial toxicology (2005)
External link to the national archive for the 2005 COT joint statement on nanomaterial toxicology
New methodologies
COT workshop on 21st century toxicology (2009)
Joint statement of the use of toxicogenomics in toxicology in toxicology (2004)
Physiologically based pharmacokinetic modelling (2003)
Symposium on the use of Genomics and Proteomics in Toxicology (2002)
Nickel
Potential risks from nickel in the diet of infants and young children (2018)
Nitrate metabolism
Nitrate metabolism in man (1999)
External link to the national archive for the 1999 COT statement on nitrate metabolism in man
O
Ochratoxin A
The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)
Ochratoxin A on dried vine fruits (1997)
Organophosphates
Statement on Organophosphates (2014)
External link to the national archive for the 2014 COT statement on Organophosphate
P
Paralytic shellfish poisoning (PSP)
Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)
Parathyroid hormone axis
Phosphate and the calcium parathyroid axis (2005)
PAVA (Nonivamide)
TW1000, a new formulation of PAVA (2018)
Use of PAVA (nonivamide) as an incapacitant spray: reformulation of captor (2007)
Combined exposure to 2-Chlorobenzylidene Malonitrile (CS) and PAVA (Nonivamide) sprays (2006)
The use of PAVA (Nonivamide) as an incapacitant spray (2004)
The use of PAVA (Nonivamide) as an incapacitant spray (2002)
Joint statement on 2-Chlorobenzylidene Malonitrile and CS spray (1999)
Peanuts
Review of the 1998 COT recommendations on peanut avoidance (2008)
Perfluorooctane
Risks from Perfluorooctane (PFOS) in the infant diet 2014
External link to the national archive for the 2014 COT statement on perfluorooctane sulfonate (PFOS)
Tolerable daily intake for perfluorooctanoic acid (2009)
Tolerable daily intake for perfluorooctanoic sulfonate (2006)
Tolerable daily intake for perfluorooctanoic acid (2006)
Pesticides
FSA-funded research and other progress on mixtures of pesticides and similar substances (2011)
Para-occupational exposure to pesticides and health outcomes (2011)
Phthalates
Dietary exposure to Phthalates - data from the Total Diet Study (2011)
Phthalates in infant formulae (1996)
External link to the national archive for the 1996 COT statement on phthalates in infant formulae
Pharmacokinetic modelling
Physiologically based pharmacokinetic modelling (2003)
Phenol
Phenol: tolerable daily intake (oral) (2002)
Phosphate
Phosphate-based flame retardants and the potential for neurodevelopmental toxicity (2019)
COT statement on phosphate-based flame retardants and the potential for neurodevelopmental toxicity
Phytoestrogens
The effects of soya phytoestrogen consumption on thyroid status (2015)
Statement on Phytoestrogens (2013)
External link to the national archive for the 2013 COT statement on Phytoestrogens
Phytoestrogens research programme (2012)
Phytoestrogens (1996)
External link to the national archive for the 1996 COT statement on phytoestrogens
Pine bark
Supplements containing French maritime pine bark extracts (1999)
Polybrominated biphenyls (PBBs) in the infant diet
Polybrominated biphenyls (PBBs) in the infant diet (2015)
Polybrominated diphenyl ethers (PBDEs)
Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)
Polybrominated diphenyl esters (PBDEs) (2015)
Polycyclic Aromatic Hydrocarbons (PAHs)
Polycyclic Aromatic Hydrocarbons - interim pragmatic guideline limits for use in emergencies (2001)
Polychlorinated dibenzo-p-dioxins (PCDDs), Polychlorinated dibenzofurans (PCDFs) and Polychlorinated biphenyls (PCBs)
Polychlorinated naphthalenes in food (2009)
Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)
Dietary exposure to dioxins and dioxin-like PCBs (2000)
Dioxins and dioxin-like PCBs in free-range eggs (2000)
Results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products (1999)
Health hazards of polychlorinated biphenyls (1997)
Potassium
Potassium-based replacements for sodium chloride and sodium-based additives (2017)
Potassium position paper (2014)
External link to the national archive for the 2014 COT position paper on potassium
Pyrrolizidine Alkaloids
Pyrrolizidine Alkaloids in Food (2008)
External link to the national archive for the 2008 COT statement on pyrrolizidine alkaloids in food
Q
No statements yet
R
Reproduction
Developmental and function in adulthood of the human male reproductive system - potential chemical-induced effects (2006)
Male reproduction (2004)
External link to the national archive for the 2004 COT statement on male reproduction
Chlorinated water and reproductive outcomes (2004)
Reproductive effects of caffeine (2001)
Chlorinated water and reproductive outcomes (1999)
Tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (1997)
Risk assessment
COT workshop on evolving approaches to chemical risk assessment (2007)
Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)
Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)
S
Salatrims / Structured triglycerides
Consideration of toxicological data for some structural triglycerides (Salatrims) composed of mixtures of short and long chain fatty acids (2000)
Toxicological aspects of submission on Salatrims, for ACNFP (1999)
Salatrims for ACNFP (1997)
Shellfish
Domoic acid in king scallops (Pecten Maximus) (2014)
Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)
Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)
Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)
Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)
Survey of mercury in fish and shellfish update (2004)
Survey of mercury in fish and shellfish (2003)
Amnesic shellfish poisoning (2001)
External link to the national archive for the 2001 COT statement on ASP
Soya
The effects of soya phytoestrogen consumption on thyroid status (2015)
Statement on Phytoestrogens (2013)
External link to the national archive for the 2013 COT statement on Phytoestrogens
Sterigmatocystin
Results of a survey for Sterigmatocystin in foodstuffs (2000)
Surveillance for the mycotoxin sterigmatocystin (1998)
Supplements
Addendum to the 2013 COT statement on potential risks from vitamin A (2017)
The possible harmful effects of high intakes of vitamin D (2014)
External link to the national archive for the 2014 COT statement on Vitamin D
High levels of vitamin A in the infant diet (2013)
External link to the national archive for the 2013 COT statement on Vitamin A
Supplements containing French maritime pine bark extracts (1999)
Preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6 (1998)
Vitamin B6 (pyridoxine) toxicity (1997)
T
Terephthalic acid
Toxicology of Terephthalic acid (2008)
Terephthalic and Isophthalic Acids from can coatings (2000)
Tetrabromobisphenol A
Tetrabromobisphenol A - review of toxicological data (2004)
Tetrachloroethylene
Tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (1997)
Tobacco
Heat not burn tobacco products (2017)
External link to the national archive for the 2017 COT statement on heat not burn tobacco products
Re - assessment of the toxicological testing of tobacco (2004)
Total diet study
2006 Total Diet Study - metals and other elements (2008)
2000 Total Diet Study - 12 metals and other elements (2004)
Arsenic in food: results of the 1999 total diet study (2003)
COT statement on fluorine in the 1997 total diet study (2003)
The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)
Tryptophan
Tryptophan And The Eosinophilia-Myalgia Syndrome (2004)
U
Uranium
Uranium levels in water used to reconstitute infant formula (2006)
V
Vitamin A
Addendum to the 2013 COT statement on potential risks from vitamin A (2017)
High levels of vitamin A in the infant diet (2013)
External link to the national archive for the 2013 COT statement on Vitamin A
Vitamin B6
Preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6 (1998)
Vitamin B6 (pyridoxine) toxicity (1997)
Vitamin D
The possible harmful effects of high intakes of vitamin D (2014)
External link to the national archive for the 2014 COT statement on Vitamin D
W
Water
Uranium levels in water used to reconstitute infant formula (2006)
Chlorinated water and reproductive outcomes (2004)
Chlorinated water and reproductive outcomes (1999)
X
No statements yet
Y
No statements yet
Z
No statements yet