Welcome to the DUMAS website!

DUal thrombolytic therapy with Mutant pro-urokinase and low dose Alteplase for ischemic Stroke

DUMAS is a phase II, randomized controlled trial in the Netherlands. This trial is initiated and coordinated by the Erasmus MC University Medical Center, Rotterdam.

DUMAS is designed to assess the safety and efficacy of dual thrombolytic treatment with mutant pro-urokinase and a low dose alteplase compared with usual treatment with alteplase alone for ischemic stroke.

The left hand menu helps you to navigate through this website and access more information about the trial.

Best regards,

The DUMAS executive committee

Diederik Dippel, Aad van der Lugt, Bob Roozenbeek, Nadinda van der Ende


Alexandre Dumas

Alexandre Dumas (24 July 1802 – 5 December 1870) was a French writer. He described the occurrence of cerebrovascular disease in several characters in his novels. An interesting analysis of cerebrovascular diseases as depicted in Dumas’ ‘The Count of Monte Cristo’ can be found here.