Yao L, D'Agostino GD, Park J, Hang S, Adhikari AA, Zhang Y, Li W, Avila-Pacheco J, Bae S, Clish CB, Franzosa EA, Huttenhower C, Huh JR, Develin AS A biosinyhtic pathway for the selective sulfonation of steroidal metabolities by human gut bacteria. Nature Microbiology 2022 Aug. doi: 10.1038/s41564-022-01176-y
Paik D, Yao L, Zhang Y, Bae S, D'Agostino G, Zhang M, Kim E, Franzosa EA, Avila-Pacheco J, Bisanz JE, Rakowski CK, Vlamakis H, Xavier RJ, Turnbaugh PJ, Longman RS, Krout MR, Clish CB, Rastinejad F, Huttenhower C, Huh JR*, Devlin AS* Human gut bacteria produce TH17-modulating bile acid metabolites. Nature. 2022 Mar. doi: 10.1038/s41586-022-04480-z
Kwon HK, Choi GB, Huh JR*. Maternal inflammation and its ramifications on fetal neurodevelopment. Trends Immunol. 2022 Mar. doi: 10.1016/j.it.2022.01.007.
Kim E, Paik D, Ramirez RN, Biggs DG, Park Y, Kwon HK, Choi GB*, Huh JR*. Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4 + T cells. Immunity. 2022 Jan 11. doi: 10.1016/j.immuni.2021.11.005.
Li W, Hang S, Fang Y, Bae S, Zhang Y, Zhang M, Wang G, McCurry MD, Bae M, Paik D, Franzosa EA, Rastinejad F, Huttenhower C, Yao L, Devlin AS*, Huh JR*. A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1. Cell Host Microbe. 2021 Sep 8. doi: 10.1016/J.chom.2021.07.013
Kalish BT*, Kim E, Finander B, Duffy EE, Kim H, Gilman CK, Yim YS, Tong L, Kaufman RJ, Griffith EC, Choi GB, Greenberg ME*, Huh JR*. Maternal immune activation in mice disrupts proteostasis in the fetal brain. Nat Neurosci. 2020 Dec 23. doi: 10.1038/s41593-020-00762-9.
Reed MD, Yim YS, Wimmer RD, Kim H, Ryu C, Welch GM, Andina M, King HO, Waisman A, Halassa MM, Huh JR*, Choi GB*. IL-17a promotes sociability in mouse models of neurodevelopmental disorders. Nature. 2019 Dec 18. doi: 10.1038/s41586-019-1843-6.
Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischach MA*, Littman DR*, Huh JR*. Bile acid meetabolites control TH17 and Treg cell differentiation. Nature. 2019 . Dec;576(7785):142-148. doi: 10.1038/s41586-019-1785-z. Epub 2019 Nov 27. PMID:31776512
Huh JR*, Veiga-Fernandes H*. Neuroimmune circuits in inter-organ comunication. Nat Rev Immunol. 2019 Dec 17. doi: 10.1038/s41577-019-0247-z. [Epub ahead of print] Review. PMID: 31848462
Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2019 Dec 3. pii: S0092-8674(19)31270-X. doi: 10.1016/j.cell.2019.11.014.
Yim YS, Park A, Berrios J, Pascual L, Soares N, Kim JY, Kim S, Kim H, Waisman A, Littman D, Harnett MT, Wickersham IR, Huh JR*, Choi GB*. Reversing behavioral abnormalities in mice exposed to maternal inflammation. Nature. 2017 doi:10.1038/nature23909
Kim S, Kim HJ, Yim YS, Ha S, Atarashi K, Tan TG, Longman RS, Honda K, Littman DR, Choi GB*, Huh JR*. Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature. 2017 doi:10.1038/nature23910.
Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA*, Littman DR*, Huh JR*. The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science. 2016 Feb 26;351(6276):933-9. PubMed PMID: 26822608; PubMed Central PMCID: PMC4782964.