Acute calcium channel blocker withdrawal-induced cardiac arrest

Neth J Med. 2019 Dec;77(9):341-343.

Abstract

Acute withdrawal of calcium channel blockers can lead to the so-called calcium channel blocker withdrawal phenomenon, in particular, when high dosages are used. In the case presented, inadequate drug substitution led to this phenomenon which resulted in a serious course of events. Careful monitoring the process of drug substitution with respect to equal therapeutic dosages is therefore a necessity, especially in vulnerable patients.

Publication types

  • Case Reports

MeSH terms

  • Angina Pectoris / drug therapy
  • Calcium Channel Blockers / administration & dosage*
  • Calcium Channel Blockers / adverse effects*
  • Coronary Vasospasm / drug therapy
  • Diagnosis, Differential
  • Female
  • Heart Arrest, Induced / methods*
  • Humans
  • Middle Aged
  • Substance Withdrawal Syndrome / drug therapy*
  • Treatment Outcome
  • Verapamil / administration & dosage*
  • Verapamil / adverse effects*

Substances

  • Calcium Channel Blockers
  • Verapamil