Authors
Jenny Yiend, Charlene LM Lam, Nora Schmidt, Bryony Crane, Margaret Heslin, Thomas Kabir, Philip McGuire, Christopher Meek, Elias Mouchlianitis, Emmanuelle Peters, Daniel Stahl, Antonella Trotta, Sukhwinder Shergill
Publication date
2023/7
Journal
Psychological medicine
Volume
53
Issue
10
Pages
4614-4626
Description
BackgroundCognitive Bias Modification for paranoia (CBM-pa) is a novel, theory-driven psychological intervention targeting the biased interpretation of emotional ambiguity associated with paranoia. Study objectives were (i) test the intervention's feasibility, (ii) provide effect size estimates, (iii) assess dose–response and (iv) select primary outcomes for future trials.MethodsIn a double-blind randomised controlled trial, sixty-three outpatients with clinically significant paranoia were randomised to either CBM-pa or an active control (text reading) between April 2016 and September 2017. Patients received one 40 min session per week for 6 weeks. Assessments were given at baseline, after each interim session, post-treatment, and at 1- and 3-months post-treatment.ResultsA total of 122 patients were screened and 63 were randomised. The recruitment rate was 51.2%, with few dropouts (four out of 63) and follow-up …
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