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Pommer S, Akamine Y, Schiffmann SN, de Kerchove d'Exaerde A, Wickens JR. The Effect of Serotonin Receptor 5-HT1B on Lateral Inhibition between Spiny Projection Neurons in the Mouse Striatum. J Neurosci. 2021 Sep 15;41(37):7831-7847. doi: 10.1523/JNEUROSCI.1037-20.2021. Epub 2021 Aug 4. PubMed PMID: 34348999; PubMed Central PMCID: PMC8445048.
Detraux B, Vilella A, De Groote A, Schiffmann SN, Zoli M, de Kerchove d'Exaerde A. Dorsal and ventral striatal neuronal subpopulations differentially disrupt male mouse copulatory behavior. Eur Neuropsychopharmacol. 2021 Aug;49:23-37. doi: 10.1016/j.euroneuro.2021.03.007. Epub 2021 Mar 26. PubMed PMID: 33780705.
Rial D, Puighermanal E, Chazalon M, Valjent E, Schiffmann SN, de Kerchove d'Exaerde A. Mammalian Target of Rapamycin-RhoA Signaling Impairments in Direct Striatal Projection Neurons Induce Altered Behaviors and Striatal Physiology in Mice. Biol Psychiatry. 2020 Dec 15;88(12):945-954. doi: 10.1016/j.biopsych.2020.05.029. Epub 2020 Jun 3. PubMed PMID: 32711953.
Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Pinto A, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA, Lopes LV. Age-related shift in LTD is dependent on neuronal adenosine A(2A) receptors interplay with mGluR5 and NMDA receptors. Mol Psychiatry. 2020 Aug;25(8):1876-1900. doi: 10.1038/s41380-018-0110-9. Epub 2018 Jun 27. PubMed PMID: 29950682; PubMed Central PMCID: PMC7387321.
Li R, Wang YQ, Liu WY, Zhang MQ, Li L, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Lazarus M, Qu WM, Huang ZL. Activation of adenosine A(2A) receptors in the olfactory tubercle promotes sleep in rodents. Neuropharmacology. 2020 May 15;168:107923. doi: 10.1016/j.neuropharm.2019.107923. Epub 2019 Dec 23. PubMed PMID: 31874169.
Dionisi C, Rai M, Chazalon M, Schiffmann SN, Pandolfo M. Primary proprioceptive neurons from human induced pluripotent stem cells: a cell model for afferent ataxias. Sci Rep. 2020 May 8;10(1):7752. doi: 10.1038/s41598-020-64831-6. PubMed PMID: 32385372; PubMed Central PMCID: PMC7210273.
Gazan A, Rial D, Schiffmann SN. Ablation of striatal somatostatin interneurons affects MSN morphology and electrophysiological properties, and increases cocaine-induced hyperlocomotion in mice. Eur J Neurosci. 2020 Mar;51(6):1388-1402. doi: 10.1111/ejn.14581. Epub 2019 Oct 14. PubMed PMID: 31549447.
Karadurmus D, Rial D, De Backer JF, Communi D, de Kerchove d'Exaerde A, Schiffmann SN. GPRIN3 Controls Neuronal Excitability, Morphology, and Striatal-Dependent Behaviors in the Indirect Pathway of the Striatum. J Neurosci. 2019 Sep 18;39(38):7513-7528. doi: 10.1523/JNEUROSCI.2454-18.2019. Epub 2019 Jul 30. PubMed PMID: 31363062; PubMed Central PMCID: PMC6750934.
Comhair J, Devoght J, Morelli G, Harvey RJ, Briz V, Borrie SC, Bagni C, Rigo JM, Schiffmann SN, Gall D, Brône B, Molchanova SM. Alpha2-Containing Glycine Receptors Promote Neonatal Spontaneous Activity of Striatal Medium Spiny Neurons and Support Maturation of Glutamatergic Inputs. Front Mol Neurosci. 2018;11:380. doi: 10.3389/fnmol.2018.00380. eCollection 2018. PubMed PMID: 30374290; PubMed Central PMCID: PMC6196267.
De Backer JF, Monlezun S, Detraux B, Gazan A, Vanopdenbosch L, Cheron J, Cannazza G, Valverde S, Cantacorps L, Nassar M, Venance L, Valverde O, Faure P, Zoli M, De Backer O, Gall D, Schiffmann SN, de Kerchove d'Exaerde A. Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine. EMBO Rep. 2018 Sep;19(9). doi: 10.15252/embr.201745089. Epub 2018 Jul 12. PubMed PMID: 30002119; PubMed Central PMCID: PMC6123657.
Molchanova SM, Comhair J, Karadurmus D, Piccart E, Harvey RJ, Rigo JM, Schiffmann SN, Brône B, Gall D. Tonically Active α2 Subunit-Containing Glycine Receptors Regulate the Excitability of Striatal Medium Spiny Neurons. Front Mol Neurosci. 2017;10:442. doi: 10.3389/fnmol.2017.00442. eCollection 2017. PubMed PMID: 29375305; PubMed Central PMCID: PMC5767327.
Laurent M, De Backer JF, Rial D, Schiffmann SN, de Kerchove d'Exaerde A. Bidirectional Control of Reversal in a Dual Action Task by Direct and Indirect Pathway Activation in the Dorsolateral Striatum in Mice. Front Behav Neurosci. 2017;11:256. doi: 10.3389/fnbeh.2017.00256. eCollection 2017. PubMed PMID: 29375331; PubMed Central PMCID: PMC5770740.
Yuan XS, Wang L, Dong H, Qu WM, Yang SR, Cherasse Y, Lazarus M, Schiffmann SN, d'Exaerde AK, Li RX, Huang ZL. Striatal adenosine A(2A) receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus. Elife. 2017 Oct 12;6. doi: 10.7554/eLife.29055. PubMed PMID: 29022877; PubMed Central PMCID: PMC5655138.
Oishi Y, Xu Q, Wang L, Zhang BJ, Takahashi K, Takata Y, Luo YJ, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Urade Y, Qu WM, Huang ZL, Lazarus M. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nat Commun. 2017 Sep 29;8(1):734. doi: 10.1038/s41467-017-00781-4. PubMed PMID: 28963505; PubMed Central PMCID: PMC5622037.
Wang YQ, Li R, Wang DR, Cherasse Y, Zhang Z, Zhang MQ, Lavielle O, McEown K, Schiffmann SN, de Kerchove d'Exaerde A, Qu WM, Lazarus M, Huang ZL. Adenosine A(2A) receptors in the olfactory bulb suppress rapid eye movement sleep in rodents. Brain Struct Funct. 2017 Apr;222(3):1351-1366. doi: 10.1007/s00429-016-1281-2. Epub 2016 Aug 2. PubMed PMID: 27485749.
De Munter S, Verheijden S, Vanderstuyft E, Malheiro AR, Brites P, Gall D, Schiffmann SN, Baes M. Early-onset Purkinje cell dysfunction underlies cerebellar ataxia in peroxisomal multifunctional protein-2 deficiency. Neurobiol Dis. 2016 Oct;94:157-68. doi: 10.1016/j.nbd.2016.06.012. Epub 2016 Jun 25. PubMed PMID: 27353294.
Lambot L, Chaves Rodriguez E, Houtteman D, Li Y, Schiffmann SN, Gall D, de Kerchove d'Exaerde A. Striatopallidal Neuron NMDA Receptors Control Synaptic Connectivity, Locomotor, and Goal-Directed Behaviors. J Neurosci. 2016 May 4;36(18):4976-92. doi: 10.1523/JNEUROSCI.2717-15.2016. PubMed PMID: 27147651; PubMed Central PMCID: PMC4854965.
Chávez M, Ena S, Van Sande J, de Kerchove d'Exaerde A, Schurmans S, Schiffmann SN. Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output. Dev Cell. 2015 Aug 10;34(3):338-50. doi: 10.1016/j.devcel.2015.06.016. Epub 2015 Jul 16. PubMed PMID: 26190144.
Bonaventura J, Navarro G, Casadó-Anguera V, Azdad K, Rea W, Moreno E, Brugarolas M, Mallol J, Canela EI, Lluís C, Cortés A, Volkow ND, Schiffmann SN, Ferré S, Casadó V. Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3609-18. doi: 10.1073/pnas.1507704112. Epub 2015 Jun 22. PubMed PMID: 26100888; PubMed Central PMCID: PMC4500251.
Wöhr M, Orduz D, Gregory P, Moreno H, Khan U, Vörckel KJ, Wolfer DP, Welzl H, Gall D, Schiffmann SN, Schwaller B. Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities. Transl Psychiatry. 2015 Mar 10;5(3):e525. doi: 10.1038/tp.2015.19. PubMed PMID: 25756808; PubMed Central PMCID: PMC4354349.
Orduz D, Boom A, Gall D, Brion JP, Schiffmann SN, Schwaller B. Subcellular structural plasticity caused by the absence of the fast Ca(2+) buffer calbindin D-28k in recurrent collaterals of cerebellar Purkinje neurons. Front Cell Neurosci. 2014;8:364. doi: 10.3389/fncel.2014.00364. eCollection 2014. PubMed PMID: 25414639; PubMed Central PMCID: PMC4220698.
Zhang JP, Xu Q, Yuan XS, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Qu WM, Urade Y, Lazarus M, Huang ZL, Li RX. Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation. Front Neuroanat. 2013;7:43. doi: 10.3389/fnana.2013.00043. eCollection 2013. PubMed PMID: 24409122; PubMed Central PMCID: PMC3857888.
Orduz D, Bischop DP, Schwaller B, Schiffmann SN, Gall D. Parvalbumin tunes spike-timing and efferent short-term plasticity in striatal fast spiking interneurons. J Physiol. 2013 Jul 1;591(13):3215-32. doi: 10.1113/jphysiol.2012.250795. Epub 2013 Apr 3. PubMed PMID: 23551945; PubMed Central PMCID: PMC3717224.
Ena SL, De Backer JF, Schiffmann SN, de Kerchove d'Exaerde A. FACS array profiling identifies Ecto-5' nucleotidase as a striatopallidal neuron-specific gene involved in striatal-dependent learning. J Neurosci. 2013 May 15;33(20):8794-809. doi: 10.1523/JNEUROSCI.2989-12.2013. PubMed PMID: 23678122; PubMed Central PMCID: PMC6618839.
Hick A, Wattenhofer-Donzé M, Chintawar S, Tropel P, Simard JP, Vaucamps N, Gall D, Lambot L, André C, Reutenauer L, Rai M, Teletin M, Messaddeq N, Schiffmann SN, Viville S, Pearson CE, Pandolfo M, Puccio H. Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia. Dis Model Mech. 2013 May;6(3):608-21. doi: 10.1242/dmm.010900. Epub 2012 Nov 7. PubMed PMID: 23136396; PubMed Central PMCID: PMC3634645.
Dardou D, Monlezun S, Foerch P, Courade JP, Cuvelier L, De Ryck M, Schiffmann SN. A role for Sv2c in basal ganglia functions. Brain Res. 2013 Apr 24;1507:61-73. doi: 10.1016/j.brainres.2013.02.041. Epub 2013 Feb 28. PubMed PMID: 23458503.
Espuny-Camacho I, Michelsen KA, Gall D, Linaro D, Hasche A, Bonnefont J, Bali C, Orduz D, Bilheu A, Herpoel A, Lambert N, Gaspard N, Péron S, Schiffmann SN, Giugliano M, Gaillard A, Vanderhaeghen P. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron. 2013 Feb 6;77(3):440-56. doi: 10.1016/j.neuron.2012.12.011. PubMed PMID: 23395372.
Schmidt H, Brachtendorf S, Arendt O, Hallermann S, Ishiyama S, Bornschein G, Gall D, Schiffmann SN, Heckmann M, Eilers J. Nanodomain coupling at an excitatory cortical synapse. Curr Biol. 2013 Feb 4;23(3):244-9. doi: 10.1016/j.cub.2012.12.007. Epub 2012 Dec 27. PubMed PMID: 23273895.
Petrinovic MM, Hourez R, Aloy EM, Dewarrat G, Gall D, Weinmann O, Gaudias J, Bachmann LC, Schiffmann SN, Vogt KE, Schwab ME. Neuronal Nogo-A negatively regulates dendritic morphology and synaptic transmission in the cerebellum. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1083-8. doi: 10.1073/pnas.1214255110. Epub 2012 Dec 31. PubMed PMID: 23277570; PubMed Central PMCID: PMC3549069.
Dubois E, Jacoby M, Blockmans M, Pernot E, Schiffmann SN, Foukas LC, Henquin JC, Vanhaesebroeck B, Erneux C, Schurmans S. Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse. Cell Signal. 2012 Nov;24(11):1971-80. doi: 10.1016/j.cellsig.2012.06.012. Epub 2012 Jun 30. PubMed PMID: 22750293.
Bischop DP, Orduz D, Lambot L, Schiffmann SN, Gall D. Control of neuronal excitability by calcium binding proteins: a new mathematical model for striatal fast-spiking interneurons. Front Mol Neurosci. 2012;5:78. doi: 10.3389/fnmol.2012.00078. eCollection 2012. PubMed PMID: 22787441; PubMed Central PMCID: PMC3392946.
Durieux PF, Schiffmann SN, de Kerchove d'Exaerde A. Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions. EMBO J. 2012 Feb 1;31(3):640-53. doi: 10.1038/emboj.2011.400. Epub 2011 Nov 8. PubMed PMID: 22068054; PubMed Central PMCID: PMC3273396.
Hourez R, Servais L, Orduz D, Gall D, Millard I, de Kerchove d'Exaerde A, Cheron G, Orr HT, Pandolfo M, Schiffmann SN. Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1. J Neurosci. 2011 Aug 17;31(33):11795-807. doi: 10.1523/JNEUROSCI.0905-11.2011. PubMed PMID: 21849540; PubMed Central PMCID: PMC6623197.
Azizieh R, Orduz D, Van Bogaert P, Bouschet T, Rodriguez W, Schiffmann SN, Pirson I, Abramowicz MJ. Progressive myoclonic epilepsy-associated gene KCTD7 is a regulator of potassium conductance in neurons. Mol Neurobiol. 2011 Aug;44(1):111-21. doi: 10.1007/s12035-011-8194-0. Epub 2011 Jun 28. PubMed PMID: 21710140.
Ena S, de Kerchove d'Exaerde A, Schiffmann SN. Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processes. Front Behav Neurosci. 2011;5:47. doi: 10.3389/fnbeh.2011.00047. eCollection 2011. PubMed PMID: 21847377; PubMed Central PMCID: PMC3148764.
Durieux PF, Schiffmann SN, de Kerchove d'Exaerde A. Targeting neuronal populations of the striatum. Front Neuroanat. 2011;5:40. doi: 10.3389/fnana.2011.00040. eCollection 2011. PubMed PMID: 21811438; PubMed Central PMCID: PMC3139926.
Dardou D, Dassesse D, Cuvelier L, Deprez T, De Ryck M, Schiffmann SN. Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system. Brain Res. 2011 Jan 7;1367:130-45. doi: 10.1016/j.brainres.2010.09.063. Epub 2010 Sep 22. PubMed PMID: 20869353.
Zhou L, Gall D, Qu Y, Prigogine C, Cheron G, Tissir F, Schiffmann SN, Goffinet AM. Maturation of "neocortex isole" in vivo in mice. J Neurosci. 2010 Jun 9;30(23):7928-39. doi: 10.1523/JNEUROSCI.6005-09.2010. PubMed PMID: 20534841; PubMed Central PMCID: PMC6632698.
Chintawar S, Hourez R, Ravella A, Gall D, Orduz D, Rai M, Bishop DP, Geuna S, Schiffmann SN, Pandolfo M. Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model. J Neurosci. 2009 Oct 21;29(42):13126-35. doi: 10.1523/JNEUROSCI.0647-09.2009. PubMed PMID: 19846700; PubMed Central PMCID: PMC6665209.
Azdad K, Chàvez M, Don Bischop P, Wetzelaer P, Marescau B, De Deyn PP, Gall D, Schiffmann SN. Homeostatic plasticity of striatal neurons intrinsic excitability following dopamine depletion. PLoS One. 2009 Sep 4;4(9):e6908. doi: 10.1371/journal.pone.0006908. PubMed PMID: 19730738; PubMed Central PMCID: PMC2733153.
Jacoby M, Cox JJ, Gayral S, Hampshire DJ, Ayub M, Blockmans M, Pernot E, Kisseleva MV, Compère P, Schiffmann SN, Gergely F, Riley JH, Pérez-Morga D, Woods CG, Schurmans S. INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse. Nat Genet. 2009 Sep;41(9):1027-31. doi: 10.1038/ng.427. Epub 2009 Aug 9. PubMed PMID: 19668215.
Durieux PF, Bearzatto B, Guiducci S, Buch T, Waisman A, Zoli M, Schiffmann SN, de Kerchove d'Exaerde A. D2R striatopallidal neurons inhibit both locomotor and drug reward processes. Nat Neurosci. 2009 Apr;12(4):393-5. doi: 10.1038/nn.2286. Epub 2009 Mar 8. PubMed PMID: 19270687.
Azdad K, Gall D, Woods AS, Ledent C, Ferré S, Schiffmann SN. Dopamine D2 and adenosine A2A receptors regulate NMDA-mediated excitation in accumbens neurons through A2A-D2 receptor heteromerization. Neuropsychopharmacology. 2009 Mar;34(4):972-86. doi: 10.1038/npp.2008.144. Epub 2008 Sep 17. PubMed PMID: 18800071; PubMed Central PMCID: PMC5527972.
Schiffmann SN. [Changes in neural networks by conditional transgenic approach: a key to our comprehension of neuro-psychiatric disorders in the basal ganglia system]. Bull Mem Acad R Med Belg. 2009;164(7-9):171-8; discussion 178-80. PubMed PMID: 20218186.
Gaspard N, Bouschet T, Hourez R, Dimidschstein J, Naeije G, van den Ameele J, Espuny-Camacho I, Herpoel A, Passante L, Schiffmann SN, Gaillard A, Vanderhaeghen P. An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature. 2008 Sep 18;455(7211):351-7. doi: 10.1038/nature07287. Epub 2008 Aug 17. PubMed PMID: 18716623.
Prestori F, Rossi P, Bearzatto B, Lainé J, Necchi D, Diwakar S, Schiffmann SN, Axelrad H, D'Angelo E. Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control. J Neurosci. 2008 Jul 9;28(28):7091-103. doi: 10.1523/JNEUROSCI.0409-08.2008. PubMed PMID: 18614678; PubMed Central PMCID: PMC6670502.
Guntz E, Dumont H, Pastijn E, d'Exaerde Ade K, Azdad K, Sosnowski M, Schiffmann SN, Gall D. Expression of adenosine A 2A receptors in the rat lumbar spinal cord and implications in the modulation of N-methyl-d-aspartate receptor currents. Anesth Analg. 2008 Jun;106(6):1882-9. doi: 10.1213/ane.0b013e318173251f. PubMed PMID: 18499627.
Bantubungi K, Blum D, Cuvelier L, Wislet-Gendebien S, Rogister B, Brouillet E, Schiffmann SN. Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease. Mol Cell Neurosci. 2008 Mar;37(3):454-70. doi: 10.1016/j.mcn.2007.11.001. Epub 2007 Nov 12. PubMed PMID: 18083596.
Ferré S, Quiroz C, Woods AS, Cunha R, Popoli P, Ciruela F, Lluis C, Franco R, Azdad K, Schiffmann SN. An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors. Curr Pharm Des. 2008;14(15):1468-74. doi: 10.2174/138161208784480108. Review. PubMed PMID: 18537670; PubMed Central PMCID: PMC2424285.
Schiffmann SN, Fisone G, Moresco R, Cunha RA, Ferré S. Adenosine A2A receptors and basal ganglia physiology. Prog Neurobiol. 2007 Dec;83(5):277-92. doi: 10.1016/j.pneurobio.2007.05.001. Epub 2007 Jun 26. Review. PubMed PMID: 17646043; PubMed Central PMCID: PMC2148496.
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