Alpha₁-Antitrypsin Deficiency

N Engl J Med. 2020 Apr 9;382(15):1443-1455. doi: 10.1056/NEJMra1910234.

Authors

Pavel Strnad¹, Noel G McElvaney¹, David A Lomas¹

Affiliation

¹ From the Department of Internal Medicine III, University Hospital RWTH (Rheinisch-Westfälisch Technische Hochschule) Aachen, Aachen, Germany (P.S.); the Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin (N.G.M.); and UCL Respiratory, Division of Medicine, Rayne Institute, University College London, London (D.A.L.).

PMID: 32268028
DOI: 10.1056/NEJMra1910234

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Graft vs Host Disease / drug therapy
Heterozygote
Humans
Liver Diseases / etiology*
Liver Diseases / physiopathology
Mutation
Pulmonary Emphysema / etiology*
Pulmonary Emphysema / physiopathology
alpha 1-Antitrypsin / therapeutic use*
alpha 1-Antitrypsin Deficiency* / complications
alpha 1-Antitrypsin Deficiency* / diagnosis
alpha 1-Antitrypsin Deficiency* / genetics
alpha 1-Antitrypsin Deficiency* / therapy

Substances

alpha 1-Antitrypsin